Internship: Master's Thesis in Bioinformatics & Data Science, Italy - 2024
Nov 15, 2023
Posting Title: Master's Thesis in Bioinformatics & Data Science Intern
Help us get ahead of disease together with our Vx Computational Design __team
Knowledge in Informatics, Computational Biology, Mathematics, Physics, Computer Science, or related fields and interest in biological research problems.
Familiarity with Artificial Intelligence and Machine Learning techniques.
Master's Student in Bioinformatics & Data Science.
Experience in Molecular Dynamics simulations is a plus.
Experience with Python and/or bash.
Basic knowledge of supercomputer calculations
Languages: Italian fluent. English desirable.
Ability to work in a multidisciplinary environment
Good communication capability
Application deadline: 28th of November
Duration: 6 Months
Start date: 8th of January 2024
Type: Curricular Internship
Looking to gain valuable real world work experience and help positively impact the health of billions of people? Apply for a GSK Internship today!
A GSK internship offers you the opportunity to kickstart your career – to take on a real role with genuine impact! You’ll take on challenging, serious work on live projects or assignments. You’ll also get to learn from us, develop your skills and gain valuable experience for wherever the future takes you.
What will you do?
The team The mission of the Discovery Data Sciences Centre of Excellence (DDS CoE) is to use high throughput technologies such as next-generation sequencing (NGS), structural biology, and advanced bioinformatics to analyze DNA sequences to answer questions about the biology and impact of vaccination on different diseases. Among the main research interests are the role of membrane composition in the function and stability of antigen-antibody complexes. To this purpose, we combine molecular dynamic simulations with state-of-the-art AI structural prediction to unveil the role of Lipopolysaccharide and Lipid membrane composition on the antibody-antigen interaction.
The aim of this proposal is to open an internship position to develop the following specific project.
“Shed light on the role of Lipopolysaccharide and Lipid membrane composition on the antibodyantigen interaction.”
Imagine having in your hand a such powerful microscope that will allow you to look inside the cell. Imagine zooming into the membrane and checking the surroundings: you would realize that membranes are flexible entities containing a large variety of lipid types and are crowded with proteins. This powerful microscope is called Molecular Dynamics (MD), an in-silico approach that allows us to overcome the current experimental limitation and investigate the effect of membrane composition on the function and stability of membrane proteins. In this project, you will go beyond the simplistic membrane representation and investigate the combined role of lipids and lipopolysaccharides on the antigen-antibody interactions. You will learn the basics of MD simulations and the cutting-edges techniques in protein and antibody structural prediction and how to critically apply in-silico techniques to reply to specific biological questions. Description The student will apply MD and AI approaches to unveil the role of membrane composition in the stability and function of the antige-antibody complex. The project will be done in the Discovery Data Science group
Let’s do this!
You’ll find hints, tips and guidance on our recruitment process on our website –
We recommend you apply as soon as possible, because we accept ongoing applications and offer positions on a first come, first served basis.
Need help with your application?
Please email us at [email protected] and let us know how we can help you.
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.
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