Flagship Pioneering, Inc.

Principal AI Scientist

Sep 16, 2023

Cambridge, England

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform human health and sustainability?

Company Summary:
FL86, Inc. is a privately held, early-stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need.

FL86 was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA) Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS). To date, Flagship has deployed over $2.5 billion in capital toward the founding and growth of its pioneering companies alongside more than $19 billion of follow-on investments from other institutions. In 2021, Flagship Pioneering was ranked 12th globally on Fortune’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies.

Position Summary: 
We are seeking a Principal AI Scientist who wants to leverage genomics data and artificial intelligence to identify new ways to treat human diseases. The candidate brings enthusiasm, intellectual curiosity, scientific rigor, and a deep-rooted desire to innovate. This role is based in the vicinity of Cambridge UK and hybrid work arrangements will be considered, but all applicants will require permission to work in UK.  

Key Responsibilities: 

  • Work with the wider scientific team to define a vision for leveraging AI/ML to further our scientific and therapeutic goals 
  • Develop and deploy AI approaches necessary to implement this vision, both directly and via leading a small team 
  • Collaborate with our data infrastructure team to ensure the data management framework is optimised to use internal and external data for AI/ML 
  • Collaborate with our wet lab team to tailor experimental design, particularly around image collection, is optimised for application of AI/ML 
  • Be an active member of a scientific team focused on the design of histology and genomics experiments, with the end goal of developing new therapeutics for diseases with large unmet needs 
  • Communicate key findings to stakeholders across the company, in written and presentation formats 
  • Collaborate closely with other members across the organization



  • PhD in genomics, computational biology, or similar discipline is required 
  • 3-7 years of industry experience applying AI to genomics data and/or target discovery 
  • Candidates with experience in (a) genomic data analysis, (b) target identification, and (c) designing new AI/ML approaches will be preferred 
  • Strong leadership, management, and collaboration skills 
  • High level of proficiency in writing python code or equivalent 
  • Excellent verbal and written communication. 
  • Ability to work successfully in a matrix environment, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively. 
  • A high degree of energy, accuracy and attention to detail, and a passion for creating transformative medicines for patients with serious diseases


Location: Cambridge, England

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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